Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | GLUL | P15104 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844113 | 0.94 | GSR (0.47) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8844273 | 0.93 | GSR (0.46) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8844107 | 0.93 | GSR (0.46) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8843499 | 0.88 | GABRR1 (0.40) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL8843534 | 0.83 | GABRR1 (0.35) | CPB2LMNACYP3A4NFKB1BLM | |
| SCHEMBL8842491 | 0.82 | FOLH1 (0.35) | LMNABLMBHMTFOLH1GLUL | |
| SCHEMBL8842798 | 0.81 | FOLH1 (0.34) | BHMTFOLH1GLUL | |
| SCHEMBL8842970 | 0.81 | FDPS (0.50) | — | |
| SCHEMBL8843633 | 0.79 | ANPEP (0.41) | LMNABLMFOLH1GLULALDH1A1 | |
| SCHEMBL8842630 | 0.79 | FDPS (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043423-C | New phosphonosuccinic acid derivatives processes for the preparation thereof and pharmaceutical compositions containing these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1999-05-19 | — | — | CN | disclosed |
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |