Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844107 | 1.00 | GSR (0.46) | GSRCPB2RNPEPLMNACYP3A4 | |
| SCHEMBL8844113 | 0.98 | GSR (0.47) | GSRCPB2RNPEPLMNACYP3A4 | |
| SCHEMBL8843565 | 0.93 | CPB2 (0.41) | GSRCPB2RNPEPLMNACYP3A4 | |
| SCHEMBL8843499 | 0.85 | GABRR1 (0.40) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL9117263 | 0.81 | GSR (0.48) | GSRCPB2RNPEPLMNACYP3A4 | |
| SCHEMBL8842798 | 0.81 | FOLH1 (0.34) | FOLH1FDPSBHMT | |
| SCHEMBL8842630 | 0.80 | FDPS (0.52) | FDPSLAP3 | |
| SCHEMBL8842491 | 0.79 | FOLH1 (0.35) | LMNABLMMEN1KMT2AFOLH1 | |
| SCHEMBL8842970 | 0.78 | FDPS (0.50) | FDPSLAP3 | |
| SCHEMBL8843534 | 0.77 | GABRR1 (0.35) | GSRCPB2RNPEPLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627170-A | Phosphonic acid compound containing heterocyclic substituents, pharmaceutical composition contains same and a method of treating calcium metabolism disturbance | BOEHRINGER MANNHEIM GMBH (DE) | 1997-05-06 | — | — | US | disclosed |
| US-5538957-A | OSTEOPOROSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-07-23 | — | — | US | disclosed |