Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752314 | 0.99 | TYMS (0.50) | TYMSPOLB | |
| SCHEMBL8059303 | 0.87 | TYMS (0.64) | TYMS | |
| Lithium Ion SCHEMBL8844141 | 0.84 | P2RY2 (0.36) | TYMSPOLB | |
| SCHEMBL6130170 | 0.84 | POLB (0.54) | TYMSPOLB | |
| SCHEMBL9497573 | 0.84 | POLB (0.56) | TYMSPOLB | |
| Deoxythymidine_Triphosphate SCHEMBL1331489 | 0.82 | POLB (0.69) | TYMSPOLB | |
| SCHEMBL28873538 | 0.82 | TYMS (0.58) | TYMSPOLB | |
| Deoxythymidine_Triphosphate SCHEMBL10698596 | 0.82 | POLB (0.69) | TYMSPOLB | |
| SCHEMBL6129083 | 0.80 | POLB (0.52) | TYMSPOLB | |
| SCHEMBL6129081 | 0.80 | POLB (0.52) | TYMSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702888-A | CONTACTING NUCLEIC ACID WITH COMPLEMENTARY NUCLEIC ACID PROBE HAVING STEROID HAPTEN BOUND THERETO BY BRIDGING GROUP TO HYBRIDIZE, CONTACTING WITH LABELLED ANTIBODY WHICH BINDS TO HAPTEN, DETECTING LABELLED ANTIBODY | BOEHRINGER MANNHEIM GMBH (DE) | 1997-12-30 | — | — | US | disclosed |
| US-5455157-A | Introducing nucleotide labelled with hapten into cell with addition of nonencapsulating cationic liposome, determining incorporation into nucleic acids as function of time | BOEHRINGER MANNHEIM GMBH (DE) | 1995-10-03 | — | — | US | disclosed |
| US-5354657-A | Incubating with detectin probe and capturing probe bound to labeled haptens and solid matrices of biotin and streptavidin | BOEHRINGER MANNHEIM GMBH (DE) | 1994-10-11 | — | — | US | disclosed |
| US-5344757-A | By hybridization with complementary, labelled nucleic acid probe which contains a steroid hapten selected from digoxin or digoxigenin | BOEHRINGER MANNHEIM GMBH (DE) | 1994-09-06 | — | — | US | disclosed |
| US-5198537-A | DIGOXIGENIN DERIVATIVES AND USE THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1993-03-30 | — | — | US | disclosed |