Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Deoxythymidine_Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS known ✓ | P04818 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | TK1 | P04183 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxythymidine_Triphosphate SCHEMBL1331489 | 1.00 | POLB (0.69) | POLBTYMSTK1 | |
| Deoxythymidine_Triphosphate SCHEMBL9437167 | 0.95 | POLB (0.74) | POLBTYMSTK1 | |
| Deoxythymidine_Triphosphate SCHEMBL22635939 | 0.94 | POLB (0.70) | POLBTYMSTK1 | |
| SCHEMBL22635987 | 0.93 | POLB (0.72) | POLBTYMSTK1 | |
| SCHEMBL9497573 | 0.90 | POLB (0.56) | POLBTYMS | |
| Thymidine Monophosphate SCHEMBL543836 | 0.90 | POLB (0.74) | POLBTYMSTK1 | |
| Deoxythymidine_Triphosphate SCHEMBL9437166 | 0.90 | POLB (0.69) | POLBTYMSTK1 | |
| Thymidine Monophosphate SCHEMBL30080151 | 0.89 | POLB (0.72) | POLBTYMSTK1 | |
| Thymidine Monophosphate SCHEMBL9687300 | 0.89 | POLB (0.72) | POLBTYMSTK1 | |
| SCHEMBL28873538 | 0.89 | TYMS (0.58) | POLBTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118853828-A | ATP (adenosine triphosphate) detection test strip based on DNA tetrahedron and preparation and detection methods thereof | 山东大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-107737339-B | Calcium phosphate-biomolecule composite material and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2021-06-15 | — | — | CN | disclosed |
| EP-0278005-A1 | DNA FOR SHUTTLE VECTOR | TAIYO KAGAKU Co., LTD. (JP) | 1988-08-17 | — | — | EP | disclosed |