Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873538 | 0.90 | TYMS (0.58) | POLBTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL10698596 | 0.90 | POLB (0.69) | POLBTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL1331489 | 0.90 | POLB (0.69) | POLBTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL9437167 | 0.86 | POLB (0.74) | POLBTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL22635939 | 0.85 | POLB (0.70) | POLBTYMS | |
| SCHEMBL4218838 | 0.85 | TYMS (0.50) | POLBTYMS | |
| SCHEMBL6660054 | 0.84 | P2RY2 (0.69) | TYMS | |
| Lithium Ion SCHEMBL9125906 | 0.84 | TYMS (0.49) | POLBTYMS | |
| Potassium Ion SCHEMBL1230628 | 0.84 | TYMS (0.58) | POLBTYMS | |
| SCHEMBL7752314 | 0.84 | TYMS (0.50) | POLBTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264346-A | Decyclization of beta-lactam ring decorizes chromophore | CHEN KIRK C S (US) | 1993-11-23 | — | — | US | claimed |
| US-5264346-A | Decyclization of beta-lactam ring decorizes chromophore | CHEN KIRK C S (US) | 1993-11-23 | — | — | US | disclosed |