Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL9482819 | 0.98 | HTR1A (0.38) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| Hydrochloric Acid SCHEMBL22031737 | 0.88 | HTR1A (0.43) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30421966 | 0.84 | HTR3A (0.33) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL435683 | 0.80 | BTK (0.39) | HTR3AUSP25 | |
| SCHEMBL29229133 | 0.80 | OPRM1 (0.41) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL23362965 | 0.80 | OPRL1 (0.38) | — | |
| SCHEMBL31703523 | 0.80 | OPRL1 (0.38) | — | |
| SCHEMBL8844136 | 0.80 | SLC6A2 (0.37) | HTR1ASLC6A2SLC6A4SLC6A3HTR3A | |
| SCHEMBL30673624 | 0.77 | HTR3A (0.38) | HTR3A | |
| SCHEMBL9901829 | 0.77 | HTR3A (0.38) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622966-A | BACTERICIDES TREATING INFECTIONS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5446044-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1995-08-29 | — | — | US | disclosed |
| US-5384407-A | Pyrrolidine compounds | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| US-5342844-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1994-08-30 | — | — | US | disclosed |
| WO-1993016077-A1 | 7-SUBSTITUTED QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-08-19 | — | — | WO | disclosed |
| US-5221676-A | 7-substituted quinolones and naphthyridones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1993-06-22 | — | — | US | disclosed |