Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14081241 | 0.92 | TUBB4A (0.43) | LMNAMAPTGAAKMT2A | |
| SCHEMBL5485044 | 0.81 | ALOX5 (0.55) | CA12CA2CA4CA7LMNA | |
| SCHEMBL29493070 | 0.81 | ALOX5 (0.55) | CA12CA2CA4CA7LMNA | |
| SCHEMBL5030552 | 0.78 | CA12 (0.56) | SMPD3CA12CA1CA2CA3 | |
| SCHEMBL514651 | 0.76 | PDE4A (0.60) | PKMLMNAMAPTTP53KMT2A | |
| SCHEMBL9238940 | 0.76 | TUBB4A (0.52) | MAPTPOLBKMT2A | |
| SCHEMBL14515226 | 0.75 | CSNK2A2 (0.53) | CA12CA2CA4CA7LMNA | |
| SCHEMBL10429139 | 0.75 | SMPD3 (0.49) | SMPD3GAAKDM4E | |
| SCHEMBL4649105 | 0.74 | ABCB1 (0.70) | CA12CA2PKMCA4CA7 | |
| SCHEMBL8843796 | 0.73 | MEN1 (0.50) | CA12CA2CA4CA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |