SCHEMBL5485044

SCHEMBL5485044

COc1cc(-c2oc(-c3ccc(O)c(OC)c3)c(C)c2C)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 5/20 0.55
▸ PTGS1 P23219 1/20 0.55
▸ PTGS2 P35354 1/20 0.55
▸ MEN1 O00255 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ MAPT P10636 2/20 0.54
▸ HPGD P15428 2/20 0.54
▸ ALOX15 P16050 2/20 0.54
▸ MAPK1 P28482 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.54
▸ GAA P10253 2/20 0.54
▸ ALOX12 P18054 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ CA12 O43570 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CYP1A1 P04798 1/20 0.52
▸ CYP1A2 P05177 1/20 0.52
▸ CA4 P22748 1/20 0.52
▸ PPARG P37231 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29493070 1.00 ALOX5 (0.55) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL14515226 0.93 CSNK2A2 (0.53) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL9238940 0.87 TUBB4A (0.52) ALOX5MEN1KMT2AMAPTCYP1A1
SCHEMBL8843796 0.87 MEN1 (0.50) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL514651 0.85 PDE4A (0.60) ALOX5MEN1KMT2ALMNAMAPT
SCHEMBL8169870 0.82 CSNK2A2 (0.47) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL3693339 0.82 MAOB (0.67) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL8843729 0.82 HTT (0.54) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL14081241 0.81 TUBB4A (0.43) ALOX5PTGS1PTGS2MEN1KMT2A
SCHEMBL8844709 0.81 SMPD3 (0.45) KMT2ALMNAMAPTGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134934-A1 FEED ADDITIVE COMPOSITIONS AND METHODS PMI NUTRITION LLC (US) 2023-05-04 — — US disclosed
US-20230134934-A1 FEED ADDITIVE COMPOSITIONS AND METHODS PMI NUTRITION LLC (US) 2023-05-04 — — US disclosed
US-20230053138-A1 FEED ADDITIVE FOR IMPROVING PERFORMANCE OF DOMESTICATED ANIMALS PMI NUTRITION LLC (US) 2023-02-16 — — US disclosed
US-20210171883-A1 ANTIVIRAL WIPER FUJIFILM CORPORATION (JP) 2021-06-10 — — US disclosed
US-7413727-B2 Contrast agents GE HEALTHCARE AS (NO) 2008-08-19 — — US disclosed
US-7413727-B2 Contrast agents GE HEALTHCARE AS (NO) 2008-08-19 — — US disclosed
US-7288413-B2 Combined chemical and immunochemical fecal occult blood test BECKMAN COULTER, INC. (US) 2007-10-30 — — US disclosed
US-20070037296-A1 Contacting the sample in an absorbent matrix with guaiaconic acid and an oxidizing agent, producing an indicator of the presence of hemoglobin and detecting the indicator; contacting with a specific binding partner for hemoglobin in a chromatographic material and detecting binding BECKMAN COULTER, INC. 2007-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171883-A1 ANTIVIRAL WIPER CGAS, PRKX, PDE4C ALOX5 1770/4885PTGS1 3289/4885PTGS2 3424/4885
US-20230053138-A1 FEED ADDITIVE FOR IMPROVING PERFORMANCE OF DOMESTICATED ANIMALS PIGS, OAT, FABP6 ALOX5 538/4885PTGS1 2279/4885PTGS2 2398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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