Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493070 | 0.87 | ALOX5 (0.55) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL5485044 | 0.87 | ALOX5 (0.55) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL14515226 | 0.81 | CSNK2A2 (0.53) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL9238940 | 0.76 | TUBB4A (0.52) | MEN1KMT2AMAPTALOX5CYP1A1 | |
| SCHEMBL8169870 | 0.74 | CSNK2A2 (0.47) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL3693339 | 0.74 | MAOB (0.67) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL14081241 | 0.74 | TUBB4A (0.43) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL514651 | 0.73 | PDE4A (0.60) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL8844709 | 0.73 | SMPD3 (0.45) | KMT2AGAALMNAMAPTKDM4E | |
| SCHEMBL4386820 | 0.72 | MAOB (0.64) | MEN1KMT2AGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7413727-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2008-08-19 | — | — | US | disclosed |
| US-7413727-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2008-08-19 | — | — | US | disclosed |
| EP-1442751-B1 | Diagnostic imaging technique | GE HEALTHCARE AS (NO) | 2007-06-20 | — | — | EP | disclosed |
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |