Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD4 | P21917 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | DRD5 | P21918 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845133 | 0.94 | HTR6 (0.66) | HTR6HTR1AHTR1DDRD2DRD4 | |
| SCHEMBL8844926 | 0.93 | HTR6 (0.64) | HTR6HTR1AHTR1DGRIN1GRIN2B | |
| SCHEMBL8844943 | 0.89 | DRD2 (0.69) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL8315052 | 0.86 | ADRA1D (0.63) | HTR1AHTR1DADRA1DADRA1AADRA1B | |
| SCHEMBL7323697 | 0.85 | HTR1A (0.61) | HTR6HTR1AHTR1DDRD2DRD4 | |
| SCHEMBL8844813 | 0.85 | HTR6 (0.63) | HTR6HTR1AHTR1D | |
| SCHEMBL7256045 | 0.83 | HTR6 (0.63) | HTR6DRD2DRD4DRD3DRD1 | |
| SCHEMBL7319400 | 0.83 | HTR1A (0.64) | HTR6HTR1AHTR1DDRD2DRD4 | |
| SCHEMBL8845143 | 0.83 | DRD2 (0.78) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL7315046 | 0.82 | DRD2 (0.64) | HTR6HTR1AHTR1DDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670667-A | DOPAMINE INHIBITORS FOR PSYCHOLOGICAL DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |