Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845522 | 0.72 | MAPT (0.42) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL8845438 | 0.72 | SMN1; SMN2 (0.44) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8845932 | 0.71 | BCHE (0.45) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8845309 | 0.70 | MAPT (0.46) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8845246 | 0.69 | KCNJ1 (0.47) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8845468 | 0.69 | CYP19A1 (0.40) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8845463 | 0.69 | KCNJ1 (0.44) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| Acetic Acid SCHEMBL6967868 | 0.68 | GAA (0.43) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8845454 | 0.67 | TGM2 (0.46) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8845195 | 0.67 | POLB (0.37) | KMT2AMEN1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5674886-A | AROMATASE INHIBITOR; BREAST CANCER; UROGENITAL DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-10-07 | — | — | US | disclosed |