SCHEMBL22046626

SCHEMBL22046626

NCc1ccc(C=C2c3ccc(O)cc3Oc3cc(O)ccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 5/20 0.48
▸ MAOA P21397 3/20 0.48
▸ TYR P14679 3/20 0.48
▸ MEN1 O00255 6/20 0.44
▸ KMT2A Q03164 6/20 0.44
▸ POLB P06746 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ ABAT P80404 1/20 0.43
▸ ELANE P08246 2/20 0.41
▸ CISD1 Q9NZ45 1/20 0.41
▸ KIT P10721 1/20 0.41
▸ RECQL P46063 2/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ PSMD14 O00487 1/20 0.41
▸ AURKA O14965 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ DAPK3 O43293 1/20 0.41
▸ JAK2 O60674 1/20 0.41
▸ STK17B O94768 1/20 0.41
▸ ALPL P05186 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22046148 0.93 MAOB (0.43) MAOBMAOATYRMEN1KMT2A
SCHEMBL22046138 0.74 MIF (0.49) MAOBMAOATYRKMT2AABAT
Isoaurostatin SCHEMBL15426107 0.74 MAOA (0.63) MAOBMAOATYRMEN1KMT2A
Isoaurostatin SCHEMBL29551912 0.74 MAOA (0.63) MAOBMAOATYRMEN1KMT2A
SCHEMBL5707799 0.67 MAOB (0.77) MAOBMAOATYRMEN1KMT2A
SCHEMBL30214414 0.65 TYR (0.86) MAOBMAOATYRMEN1KMT2A
SCHEMBL28949991 0.65 TYR (0.86) MAOBMAOATYRMEN1KMT2A
SCHEMBL29435856 0.65 TYR (1.00) MAOBMAOATYRMEN1KMT2A
SCHEMBL30214422 0.65 TYR (1.00) MAOBMAOATYRMEN1KMT2A
SCHEMBL5707753 0.65 TYR (1.00) MAOBMAOATYRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2023-11-21 — — US disclosed
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. (US) 2022-02-01 — — US disclosed
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION AAT BIOQUEST, INC. (US) 2020-12-03 — — US disclosed
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection AAT BIOQUEST, INC. 2020-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11821901-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MAOB 272/4885MAOA 1625/4885TYR 72/4885
US-20200174006-A1 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MAOB 272/4885MAOA 1625/4885TYR 72/4885
US-11237170-B2 Styryl phenols, derivatives and their use in methods of analyte detection STUB1, SPR, HLCS MAOB 272/4885MAOA 1625/4885TYR 72/4885
US-20200378975-A1 STYRYL PHENOLS, DERIVATIVES AND THEIR USE IN METHODS OF ANALYTE DETECTION STUB1, SPR, HLCS MAOB 272/4885MAOA 1625/4885TYR 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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