Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845630 | 0.97 | KMT2A (0.47) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL11654298 | 0.86 | LMNA (0.53) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL8845447 | 0.83 | ADK (0.46) | KMT2AMAPTHTTTDP1ALDH1A1 | |
| SCHEMBL8845778 | 0.77 | TSHR (0.44) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL25809403 | 0.74 | KMT2A (0.51) | KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL11719130 | 0.74 | TSHR (0.48) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL10453658 | 0.73 | TSHR (0.59) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL11142653 | 0.73 | TSHR (0.59) | KMT2AMAPTSMN1; SMN2MEN1GAA | |
| SCHEMBL4874795 | 0.72 | KMT2A (0.57) | KMT2AMAPTGAALMNA | |
| SCHEMBL24622129 | 0.72 | KMT2A (0.51) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703215-A | SOLID WATER SOLUBLE DYE CONTAINING ELECTROPHILIC AND NUCLEOPHILIC GROUPS, WHICH WHEN HEATED AND/OR BASIFIED CAUSES FORMATION OF COVALENT BONDS BETWEEN SAID GROUPS ON DIFFERENT MOLECULES | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| US-5474580-A | Applying to substrate a mixture of water and water soluble dye containing nucleophilic and electrophilic group, heating or basifying to cause molecule of dyes to join together | ZENECA LIMITED (GB) | 1995-12-12 | — | — | US | disclosed |