Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845458 | 0.83 | KMT2A (0.43) | KMT2APOLBALDH1A1TDP1MAPT | |
| SCHEMBL12513085 | 0.82 | HTR7 (0.47) | ADKKMT2ANPC1POLBSLC2A1 | |
| SCHEMBL8845630 | 0.80 | KMT2A (0.47) | KMT2ARAD52ALDH1A1TDP1MAPT | |
| SCHEMBL24622129 | 0.77 | KMT2A (0.51) | KMT2A | |
| SCHEMBL5486033 | 0.77 | KMT2A (0.51) | KMT2A | |
| SCHEMBL25809403 | 0.73 | KMT2A (0.51) | KMT2ARAD52MAPT | |
| SCHEMBL20511434 | 0.73 | HPGD (0.62) | NFKB1 | |
| SCHEMBL11988210 | 0.73 | SYK (0.43) | ADKKMT2ANPC1POLBSLC2A1 | |
| SCHEMBL11654298 | 0.72 | LMNA (0.53) | KMT2APOLBNFKB1ALDH1A1MAPT | |
| SCHEMBL1268734 | 0.72 | L3MBTL1 (0.47) | ADKKMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703215-A | SOLID WATER SOLUBLE DYE CONTAINING ELECTROPHILIC AND NUCLEOPHILIC GROUPS, WHICH WHEN HEATED AND/OR BASIFIED CAUSES FORMATION OF COVALENT BONDS BETWEEN SAID GROUPS ON DIFFERENT MOLECULES | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| US-5474580-A | Applying to substrate a mixture of water and water soluble dye containing nucleophilic and electrophilic group, heating or basifying to cause molecule of dyes to join together | ZENECA LIMITED (GB) | 1995-12-12 | — | — | US | disclosed |
| EP-0639237-A1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES. | ZENECA LTD (GB) | 1995-02-22 | — | — | EP | disclosed |
| WO-1994012717-A1 | DYES, THEIR PREPARATION AND USE IN THE COLORATION OF SUBSTRATES | ZENECA LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |