Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | G6PC1 | P35575 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413430 | 0.87 | G6PC1 (0.52) | TSHRG6PC1ALDH1A1CA12CA9 | |
| SCHEMBL11695902 | 0.81 | TDP1 (0.46) | TSHRG6PC1ALDH1A1CA12CA9 | |
| SCHEMBL11697442 | 0.79 | G6PC1 (0.47) | TSHRG6PC1ALDH1A1CA12CA9 | |
| N-Nitrosodiethylamine SCHEMBL9016304 | 0.77 | TSHR (0.81) | TSHRALDH1A1 | |
| SCHEMBL22614351 | 0.76 | CA12 (0.47) | LMNATSHRG6PC1ALDH1A1CA12 | |
| SCHEMBL29049158 | 0.75 | G6PC1 (0.46) | TSHRG6PC1ALDH1A1CA12CA9 | |
| SCHEMBL1350144 | 0.75 | ALDH1A1 (0.47) | LMNATSHRG6PC1ALDH1A1CA12 | |
| SCHEMBL1165535 | 0.74 | TSHR (0.56) | LMNATSHRALDH1A1CA12CA9 | |
| SCHEMBL81248 | 0.70 | HRH3 (0.65) | LMNATSHRALDH1A1KDM4ECNR2 | |
| SCHEMBL11214749 | 0.70 | TSHR (0.58) | LMNATSHRALDH1A1KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053317-A | N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND | TEIJIN LIMITED (JA) | 1977-10-11 | — | — | US | claimed |
| WO-2017045648-A1 | PREPARATION METHOD FOR DEUTERATED COMPOUND | 正大天晴药业集团股份有限公司 | 2017-03-23 | — | — | WO | disclosed |
| EP-0428342-B1 | Stable thiol-ene compositions | LOCTITE IRELAND LTD (IE) | 1997-01-15 | — | — | EP | disclosed |
| US-5358976-A | Curable; stabilization by addition of a non-acidic N-nitroso compound | LOCTITE (IRELAND) LIMITED (IE) | 1994-10-25 | — | — | US | disclosed |
| EP-0484054-A1 | Stabilised thiol-ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0428342-A2 | Stable thiol-ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1991-05-22 | — | — | EP | disclosed |
| US-4053317-A | N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND | TEIJIN LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |