Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195174 | 0.81 | SLC6A2 (1.00) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL9201233 | 0.78 | SLC6A2 (0.70) | SLC6A2SLC6A4CYP17A1 | |
| SCHEMBL8845768 | 0.77 | SLC6A2 (0.68) | SLC6A2SLC6A4CYP17A1ALDH1A1MAPT | |
| SCHEMBL9197969 | 0.75 | SLC6A2 (0.65) | SLC6A2SLC6A4CYP17A1MAPT | |
| SCHEMBL9192640 | 0.69 | SLC6A2 (0.57) | SLC6A2MAPT | |
| SCHEMBL9194455 | 0.69 | SLC6A2 (0.63) | SLC6A2SLC6A4 | |
| SCHEMBL2596677 | 0.69 | — | — | |
| SCHEMBL9155328 | 0.69 | SLC6A2 (0.56) | SLC6A2 | |
| SCHEMBL8845539 | 0.69 | SLC6A2 (0.56) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL9198615 | 0.67 | SLC6A2 (0.59) | SLC6A2SLC6A4CYP17A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |