Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.42 |
| ▸ | ITGAV | P06756 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845716 | 0.89 | SLC6A2 (0.55) | SLC6A2ITGB3ITGAVMAOAMAOB | |
| SCHEMBL8845539 | 0.86 | SLC6A2 (0.56) | SLC6A2ITGB3ITGAVMAOAITGB5 | |
| SCHEMBL9197969 | 0.82 | SLC6A2 (0.65) | SLC6A2ITGB3ITGAV | |
| SCHEMBL9196729 | 0.82 | SLC6A2 (0.52) | SLC6A2ITGB3ITGAVCNR2MEN1 | |
| SCHEMBL8845725 | 0.80 | SLC6A2 (0.54) | SLC6A2ITGB3ITGAVCNR2ITGB5 | |
| SCHEMBL8845540 | 0.80 | SLC6A2 (0.49) | SLC6A2ITGB3ITGAVKMT2AITGB5 | |
| Oxalic Acid SCHEMBL9196754 | 0.79 | SLC6A2 (0.57) | SLC6A2ITGB3ITGAVMEN1KMT2A | |
| SCHEMBL8845768 | 0.78 | SLC6A2 (0.68) | SLC6A2ITGB3ITGAVMEN1KMT2A | |
| SCHEMBL9201233 | 0.77 | SLC6A2 (0.70) | SLC6A2ITGB3ITGAV | |
| SCHEMBL9194455 | 0.76 | SLC6A2 (0.63) | SLC6A2ITGB3ITGAVMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471298-B1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST ROUSSEL PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| US-5455245-A | Alzheimer*s disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5264442-A | For treating alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0471298-A1 | Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-02-19 | — | — | EP | disclosed |