Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625616 | 0.84 | AR (0.44) | TSHRKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL3376658 | 0.83 | ALDH1A1 (0.49) | SMN1; SMN2TSHRNPC1RAB9ANPSR1 | |
| SCHEMBL31156292 | 0.77 | IKBKB (0.47) | — | |
| SCHEMBL20147802 | 0.75 | ADORA1 (0.52) | SMN1; SMN2TSHRNPC1RAB9AKMT2A | |
| SCHEMBL7271852 | 0.75 | KDM4E (0.50) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL1841291 | 0.74 | TSHR (0.59) | SMN1; SMN2TSHRNPC1RAB9ANPSR1 | |
| SCHEMBL21189094 | 0.74 | ADRA2C (0.49) | CYP1A2CYP2C19KDM4EADORA2AADORA1 | |
| SCHEMBL102473 | 0.73 | CYP1A2 (0.59) | TSHRKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL23200373 | 0.73 | CYP1A2 (0.47) | TSHRRAB9ANPSR1CYP1A2CYP2C19 | |
| SCHEMBL584047 | 0.72 | CYP1A2 (0.50) | SMN1; SMN2TSHRNPSR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333542-A | Preparation method of high-temperature brominated sartanbiphenyl based on bromine | 嘉兴学院 | 2020-06-26 | — | — | CN | claimed |
| CN-111320555-A | Preparation method of normal-temperature brominated sartanbiphenyl based on dibromohydantoin | 嘉兴学院 | 2020-06-23 | — | — | CN | claimed |
| CN-111302973-A | Preparation method of normal-temperature brominated sartanbiphenyl based on bromine | 嘉兴学院 | 2020-06-19 | — | — | CN | claimed |
| CN-111333542-A | Preparation method of high-temperature brominated sartanbiphenyl based on bromine | 嘉兴学院 | 2020-06-26 | — | — | CN | disclosed |
| CN-111333540-A | Preparation method of high-temperature bromosartanbiphenyl based on sodium bromide-sodium bromate system | 嘉兴学院 | 2020-06-26 | — | — | CN | disclosed |
| CN-104072386-A | Improvement method of valsartan intermediate | ZHEJIANG HUAHAI PHARM CO LTD | 2014-10-01 | — | — | CN | disclosed |
| US-5610301-A | Process for the regioselective n-alkylation of quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1997-03-11 | — | — | US | disclosed |