Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CPS1 | P31327 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371452 | 0.87 | NPC1 (0.59) | MAPTCES2CES1NPC1RAB9A | |
| SCHEMBL5359509 | 0.86 | RAB9A (0.61) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4456955 | 0.81 | NPC1 (0.59) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14324280 | 0.80 | ALDH1A1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8175818 | 0.78 | HTT (0.59) | MAPK14MAPTCES2CES1NPC1 | |
| SCHEMBL490044 | 0.78 | RAB9A (0.73) | MAPK14MAPTCES2CES1NPC1 | |
| SCHEMBL29880739 | 0.77 | CES2 (0.63) | MAPK14CES2CES1RAB9ASMN1; SMN2 | |
| SCHEMBL8609990 | 0.77 | CES2 (0.63) | MAPK14CES2CES1RAB9ASMN1; SMN2 | |
| SCHEMBL13291390 | 0.76 | CES2 (0.74) | MAPK14CES2CES1NPC1RAB9A | |
| SCHEMBL8178069 | 0.75 | MAPK14 (0.52) | MAPK14MAPTCES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600317-B1 | Process for the preparation of halogenated benzoic acids | HOECHST AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| US-5481032-A | Process for the preparation of halogenated benzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-02 | — | — | US | disclosed |
| EP-0600317-A1 | Process for the preparation of halogenated benzoic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |