Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13328484 | 0.77 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTALOX15RECQL | |
| SCHEMBL48345 | 0.77 | ALDH1A1 (0.62) | ALDH1A1POLBMAPTALOX15RECQL | |
| SCHEMBL11088882 | 0.76 | ALDH1A1 (0.35) | ALDH1A1POLBMAPTALOX15RECQL | |
| SCHEMBL3043384 | 0.74 | POLB (0.44) | ALDH1A1POLBMAPTALOX15RECQL | |
| SCHEMBL7567519 | 0.74 | KDM4E (0.36) | — | |
| SCHEMBL12589712 | 0.73 | SIGMAR1 (0.50) | ALDH1A1 | |
| SCHEMBL13328480 | 0.73 | ALDH1A1 (0.46) | ALDH1A1POLBMAPT | |
| SCHEMBL13328482 | 0.72 | ALDH1A1 (0.45) | ALDH1A1POLB | |
| SCHEMBL15834123 | 0.71 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTALOX15 | |
| SCHEMBL26210630 | 0.71 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755262-A4 | COMPOSITION FOR THE TREATMENT OF LUNG DISEASE | MERCK & CO INC (US) | 1997-05-07 | — | — | EP | disclosed |
| EP-0755262-A1 | COMPOSITION FOR THE TREATMENT OF LUNG DISEASE | MERCK & CO. INC. (US) | 1997-01-29 | — | — | EP | disclosed |