SCHEMBL8846148

SCHEMBL8846148

Nc1ccccc1OO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28259789 0.79 CD44 (0.42)
SCHEMBL6889015 0.78 CA2 (0.44)
SCHEMBL29508342 0.77 KDM4E (0.65)
SCHEMBL81185 0.77 KDM4E (0.65)
SCHEMBL863708 0.77 ALDH1A1 (0.62)
SCHEMBL30979203 0.77 KDM4E (0.65)
SCHEMBL2285909 0.76 GAA (0.69)
SCHEMBL6289306 0.74 KDM4E (0.62)
SCHEMBL1361220 0.74 KDM4E (0.62)
SCHEMBL6293125 0.74 KDM4E (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9202753-A None JP disclosed
EP-2797592-B1 COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY PTC THERAPEUTICS INC (US) 2019-08-28 EP disclosed
JP-H09202753-A PHENOXY-2-AMINOALCOHOL DERIVATIVE AND ITS PRODUCTION UBE IND LTD 1997-08-05 JP disclosed