Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7940168 | 0.81 | ALDH1A1 (0.32) | MEN1KMT2ACA1CA2CA4 | |
| SCHEMBL8846019 | 0.77 | TNF (0.33) | NPC1RAB9A | |
| SCHEMBL8846028 | 0.69 | HSPA1A (0.45) | MEN1KMT2A | |
| SCHEMBL8730366 | 0.68 | CA1 (0.37) | CA1CA2CA4 | |
| SCHEMBL10338047 | 0.65 | KDM4E (0.41) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL18535556 | 0.65 | ALDH1A1 (0.31) | MEN1RAB9AKMT2A | |
| SCHEMBL1995798 | 0.65 | CA1 (0.41) | CA1CA2CA4CA12CA7 | |
| SCHEMBL14560530 | 0.64 | SMN1; SMN2 (0.41) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL23027211 | 0.62 | ALDH1A1 (0.48) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14560532 | 0.62 | PTGS2 (0.39) | MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563986-B1 | Process for selective hydrodefluorination | OCCIDENTAL CHEM CO (US) | 1997-09-03 | — | — | EP | disclosed |
| US-5294738-A | Hydrolysis of imide and hydrodefluorination | OCCIDENTAL CHEMICAL CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0563986-A2 | Process for selective hydrodefluorination | Occidental Chemical Corporation (US) | 1993-10-06 | — | — | EP | disclosed |