Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.43 |
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845756 | 0.84 | HTR2C (0.39) | KDM4EALDH1A1HTR2CHTR2BHTR2A | |
| SCHEMBL16494652 | 0.75 | ACHE (0.63) | ACHEBCHE | |
| SCHEMBL16494866 | 0.75 | BCHE (0.55) | ACHEBCHE | |
| SCHEMBL8845546 | 0.75 | ITGB3 (0.48) | ALDH1A1 | |
| SCHEMBL16494279 | 0.75 | EGFR (0.52) | ACHEBCHEALDH1A1MEN1KMT2A | |
| SCHEMBL16494107 | 0.74 | ACHE (0.50) | ACHEKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL16494699 | 0.74 | ACHE (0.55) | ACHEKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8845548 | 0.74 | ACHE (0.51) | ACHEBCHE | |
| SCHEMBL16494166 | 0.73 | FAAH (0.49) | ACHEBCHEALDH1A1 | |
| SCHEMBL16494308 | 0.73 | TNF (0.49) | ACHEBCHEKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688816-A | COGNITION ACTIVATOR; ALZHEIMER'S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-18 | — | — | US | disclosed |