SCHEMBL8846624

SCHEMBL8846624

CC(S)(CC(O)CO)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.35
ACACA Q13085 1/20 0.35
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
OR51E2 Q9H255 1/20 0.33
MAPT P10636 1/20 0.33
PTGS1 P23219 1/20 0.33
TSHR P16473 2/20 0.32
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL17363584 0.78 ALDH1A1 (0.47) ACACBACACAALDH1A1LMNAOR51E2
Glycerin SCHEMBL11231404 0.78 ALDH1A1 (0.47) ACACBACACAALDH1A1LMNAOR51E2
SCHEMBL7698392 0.76 ACACB (0.47) ACACBACACAALDH1A1LMNAOR51E2
SCHEMBL19457910 0.76 LMNA (0.38) ALDH1A1LMNAOR51E2
SCHEMBL27772448 0.76 GRM2 (0.36) ALDH1A1MAPTPTGS1TSHRCYP2D6
SCHEMBL222489 0.74 TET2 (0.45) ACACBACACAALDH1A1LMNAOR51E2
Thioglycolic Acid SCHEMBL27469079 0.74 LMNA (0.37) ACACBACACAALDH1A1LMNAOR51E2
Ethylene Glycol SCHEMBL17512162 0.73 LMNA (0.35) ALDH1A1LMNAOR51E2
SCHEMBL6003775 0.73 ACACB (0.35) ACACBACACAALDH1A1LMNAOR51E2
SCHEMBL25660522 0.73 GGT1 (0.42) ACACBACACAALDH1A1LMNAOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5241973-A Mercaptopolyoxyethylene compound as posttreatment or additive; durability SHISEIDO (JP) 1993-09-07 US claimed
US-5617883-A A LOTION COMPRISING GLYCERYL MONOTHIOPROPIONATE, GLYCERYL THIOLACTATE; ODORLESS, DURABILITY SHISEIDO CO., LTD. (JP) 1997-04-08 US disclosed
US-5350572-A Polyoxyethylene dimercaptoalkyl ester SHISEIDO CO., LTD. (JP) 1994-09-27 US disclosed
US-5241973-A Mercaptopolyoxyethylene compound as posttreatment or additive; durability SHISEIDO (JP) 1993-09-07 US disclosed