Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846503 | 0.85 | PPARD (0.60) | GAAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL8846760 | 0.85 | MEN1 (0.61) | GAAALOX12MEN1KMT2ALMNA | |
| SCHEMBL8846787 | 0.84 | USP2 (0.62) | ALDH1A1MEN1KMT2ALMNANPC1 | |
| SCHEMBL8846641 | 0.82 | PRMT5 (0.46) | ALDH1A1TP53MEN1KMT2ANPC1 | |
| SCHEMBL8846658 | 0.79 | MAPT (0.60) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8846600 | 0.78 | HPGD (0.68) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9151895 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ANPC1USP2 | |
| SCHEMBL7508983 | 0.74 | HIF1A (0.52) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL22227971 | 0.73 | ALDH1A1 (0.66) | GAAALOX12ALDH1A1NOTUMTP53 | |
| SCHEMBL30602658 | 0.73 | ALDH1A1 (0.66) | GAAALOX12ALDH1A1NOTUMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |