Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846503 | 0.85 | PPARD (0.60) | PPARDHPGDHTTKMT2AMEN1 | |
| SCHEMBL8846839 | 0.82 | GAA (0.50) | PPARDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL8846787 | 0.81 | USP2 (0.62) | MTNR1AMTNR1BHPGDCYP1A2CYP2C9 | |
| SCHEMBL13627123 | 0.79 | RAB9A (0.59) | PRMT5MTNR1AMTNR1BHPGDKDM4E | |
| SCHEMBL8846760 | 0.74 | MEN1 (0.61) | CYP1A2CYP2C9CYP2C19KDM4ENPC1 | |
| SCHEMBL7508983 | 0.74 | HIF1A (0.52) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL9151895 | 0.72 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19KDM4ENPC1 | |
| SCHEMBL8846863 | 0.72 | HSD17B10 (0.70) | MTNR1AMTNR1BHPGDKMT2ANPSR1 | |
| SCHEMBL7996336 | 0.72 | LMNA (0.63) | MTNR1AMTNR1BKDM4EHTTKMT2A | |
| SCHEMBL29955055 | 0.72 | LMNA (0.63) | MTNR1AMTNR1BKDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |