Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846760 | 0.86 | MEN1 (0.61) | NPC1CYP2C9CYP2C19CYP1A2KDM4E | |
| SCHEMBL8846503 | 0.84 | PPARD (0.60) | HPGDKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8846839 | 0.84 | GAA (0.50) | USP2NPC1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL9151895 | 0.84 | ALDH1A1 (0.49) | USP2NPC1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8846641 | 0.81 | PRMT5 (0.46) | USP2NPC1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8846600 | 0.81 | HPGD (0.68) | HPGDTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL8846863 | 0.81 | HSD17B10 (0.70) | HPGDTSHRKMT2AALDH1A1MAPT | |
| SCHEMBL8846603 | 0.79 | MEN1 (0.49) | NPC1CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL9152090 | 0.79 | PTGDR2 (0.51) | USP2NPC1CYP2C9CYP2C19KDM4E | |
| SCHEMBL9868600 | 0.79 | CYP1A2 (0.89) | USP2NPC1CYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | claimed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | claimed |
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |