Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846839 | 0.85 | GAA (0.50) | PPARDKMT2AMEN1HTTGAA | |
| SCHEMBL8846641 | 0.85 | PRMT5 (0.46) | PPARDKMT2AMEN1HTTMAPT | |
| SCHEMBL8846787 | 0.84 | USP2 (0.62) | KMT2AMEN1POLBHTTMAPT | |
| SCHEMBL7508983 | 0.79 | HIF1A (0.52) | KMT2AMEN1POLBMAPTMAPK1 | |
| SCHEMBL13458590 | 0.77 | KMT2A (0.67) | PPARDKMT2AMEN1HSD17B10POLB | |
| SCHEMBL8846760 | 0.77 | MEN1 (0.61) | KMT2AMEN1HTTMAPTGAA | |
| SCHEMBL16384637 | 0.77 | ALDH1A1 (0.63) | PPARDKMT2AMEN1HSD17B10POLB | |
| SCHEMBL22040865 | 0.75 | PPARD (1.00) | PPARDKMT2AMEN1HSD17B10POLB | |
| SCHEMBL26382364 | 0.75 | PPARD (0.83) | PPARDKMT2AMEN1HSD17B10POLB | |
| SCHEMBL9151895 | 0.75 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |