Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29703387 | 0.87 | MAPT (0.40) | ALDH1A1NPC1RAB9AALOX12MAPT | |
| SCHEMBL17993036 | 0.87 | MAPT (0.40) | ALDH1A1NPC1RAB9AALOX12MAPT | |
| SCHEMBL4069517 | 0.81 | L3MBTL1 (0.40) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL836038 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1NCEH1HPGD | |
| SCHEMBL3483598 | 0.79 | ALDH1A1 (0.41) | ALDH1A1RAB9AMAPTL3MBTL1HPGD | |
| SCHEMBL3493073 | 0.78 | PTGDR2 (0.54) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL2874915 | 0.77 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL28186675 | 0.77 | PKM (0.44) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL7391480 | 0.76 | PTGDR2 (0.49) | ALDH1A1ALOX12MAPTL3MBTL1NCEH1 | |
| SCHEMBL10896908 | 0.76 | RAB9A (0.59) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406478-A | ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS | 格莱克特生物技术公司 | 2017-11-28 | — | — | CN | disclosed |
| US-5626792-A | DIPHENYLACETYLENE ESTERS, THIOESTERS OR DITHIOESTERS | DISPLAYTECH, INC. (US) | 1997-05-06 | — | — | US | disclosed |