Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11303568 | 0.83 | PTPN1 (0.54) | ALDH1A1RAB9ASMN1; SMN2NPC1CHRM4 | |
| SCHEMBL31109115 | 0.77 | PTPN1 (0.60) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8375785 | 0.76 | MTNR1A (0.54) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5617855 | 0.76 | RAB9A (0.47) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8378803 | 0.76 | CHRM4 (0.50) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8375531 | 0.76 | RAB9A (0.47) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27810220 | 0.76 | ALDH1A1 (0.56) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8375006 | 0.76 | RAB9A (0.46) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8380154 | 0.76 | SMN1; SMN2 (0.55) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11639996 | 0.75 | NPC1 (0.58) | ALDH1A1RAB9AKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641768-B1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5580893-A | TREATMENT AND PREVENTION OF ANGINA PECTORIS; SIDE-EFFECT REDUCTION; VASODILATION | SANKYO COMPANY, LIMITED (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0641768-A1 | NITROXYALKYLAMIDE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |