Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847298 | 0.87 | PTGS2 (0.31) | LMNA | |
| SCHEMBL8847199 | 0.79 | PTGS1 (0.31) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8847552 | 0.79 | LMNA (0.36) | LMNA | |
| SCHEMBL23794707 | 0.78 | S1PR2 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8847307 | 0.77 | KCNH2 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8847221 | 0.75 | HTR2A (0.41) | LMNABLM | |
| SCHEMBL14399649 | 0.72 | CA2 (0.39) | PTGS1PDE4A | |
| SCHEMBL778663 | 0.72 | DAO (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL30512240 | 0.72 | ACP1 (0.42) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8847296 | 0.72 | TBXAS1 (0.35) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603557-B1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM CO (US) | 1997-07-30 | — | — | EP | disclosed |
| US-5461126-A | Process of polymerizing olefins using organonickel catalyst compositions | PHILLIPS PETROLEUM COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| US-5332708-A | Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0603557-A1 | Catalyst compositions and catalytic processes | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |