SCHEMBL8847334

SCHEMBL8847334

CC(C)(c1ccccc1)c1ccc(C(OC(c2ccc(C(C)(C)c3ccccc3)cc2)C2CO2)C2CO2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
ALDH1A1 P00352 2/20 0.41
ESR1 P03372 1/20 0.41
CYP3A4 P08684 1/20 0.41
ESR2 Q92731 1/20 0.41
TP53 P04637 2/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
TSHR P16473 2/20 0.40
CYP1A2 P05177 1/20 0.40
PPARG P37231 1/20 0.40
HIF1A Q16665 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.36
NR3C2 P08235 3/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
MAPK1 P28482 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL266494 0.83 TSHR (0.34) KMT2AMEN1ALDH1A1TP53MAPT
SCHEMBL3687682 0.81 IDO1 (0.44) TSHRSLC6A2SLC6A4CHRM2CHRM4
SCHEMBL151181 0.81 IDO1 (0.44) TSHRSLC6A2SLC6A4CHRM2CHRM4
SCHEMBL8677979 0.79 CHRM2 (0.34) KMT2AMEN1SLC6A2SLC6A4CHRM2
SCHEMBL8677213 0.79 CHRM2 (0.34) KMT2AMEN1SLC6A2SLC6A4CHRM2
SCHEMBL7867600 0.78 EPHX1 (0.41) ALDH1A1CYP3A4
SCHEMBL10411363 0.77 SHBG (0.42) KMT2AMEN1ALDH1A1CYP3A4TP53
SCHEMBL28635190 0.76 LTA4H (0.41) TSHRSLC6A2SLC6A4
SCHEMBL3784692 0.74 CHRNA7 (0.39) KMT2AMEN1SLC6A2SLC6A4
SCHEMBL8847061 0.74 MGLL (0.42) SLC6A2SLC6A4CHRM2CHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605937-B1 Antistatic resin composition DAISO CO LTD (JP) 1997-06-11 EP claimed