Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | IAPP | P10997 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 7/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847721 | 1.00 | MMP2 (0.46) | MMP2MMP9MMP8NFKB1ALDH1A1 | |
| SCHEMBL28734267 | 0.84 | PTGS1 (0.43) | MMP2MMP9MMP8NFKB1ALDH1A1 | |
| SCHEMBL8847575 | 0.83 | IAPP (0.59) | ALDH1A1CYP3A4RECQLIAPPAPP | |
| SCHEMBL9682413 | 0.83 | IAPP (0.59) | ALDH1A1CYP3A4RECQLIAPPAPP | |
| SCHEMBL28720493 | 0.81 | PTGS1 (0.41) | ALDH1A1CYP3A4RECQLIAPPAPP | |
| SCHEMBL29722134 | 0.81 | PTGS1 (0.41) | MMP2MMP9MMP8NFKB1ALDH1A1 | |
| SCHEMBL6056797 | 0.81 | BACE1 (0.48) | ALDH1A1CYP3A4RECQLIAPPAPP | |
| SCHEMBL6056802 | 0.81 | BACE1 (0.48) | ALDH1A1CYP3A4RECQLIAPPAPP | |
| SCHEMBL8409048 | 0.80 | TNNC1 (0.41) | MMP2MMP9NFKB1ALDH1A1CYP3A4 | |
| SCHEMBL12692553 | 0.80 | ALDH1A1 (0.69) | MMP2MMP9MMP8NFKB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610169-A | Pharmaceutical Composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5462951-A | Dissolved in a polyoxyethylene sorbitan fatty acid ester and adsorbed onto a porosity inorganic substance | THE GREEN CROSS CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0448091-A2 | Pharmaceutical composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1991-09-25 | — | — | EP | disclosed |