Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309536 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MMP2MMP9MMP14MMP8 | |
| SCHEMBL8308800 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MMP2MMP9MMP14MMP8 | |
| SCHEMBL8308796 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2MMP2MMP9MMP14MMP8 | |
| SCHEMBL8886064 | 0.84 | MMP2 (0.40) | SMN1; SMN2MMP2MMP9MMP14MMP8 | |
| SCHEMBL8888095 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1RAB9ATDP1GAA | |
| SCHEMBL516278 | 0.77 | TDP1 (0.56) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL8886446 | 0.74 | MGLL (0.45) | SMN1; SMN2HTT | |
| SCHEMBL8848438 | 0.74 | CHRNB2 (0.40) | ALDH1A1MAPTGAAATML3MBTL1 | |
| SCHEMBL8848447 | 0.74 | CHRNB2 (0.40) | ALDH1A1MAPTGAAATML3MBTL1 | |
| SCHEMBL8848434 | 0.74 | CHRNB2 (0.40) | ALDH1A1MAPTGAAATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |