Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848722 | 0.86 | RAB9A (0.65) | LTA4HMAOBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8848741 | 0.84 | MAOB (0.52) | LTA4HMAOBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8848788 | 0.80 | MEN1 (0.64) | LTA4HNPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL8848700 | 0.80 | SMN1; SMN2 (0.50) | LTA4HNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8848545 | 0.80 | RAB9A (0.52) | NPC1RAB9AL3MBTL1ELANETHRB | |
| SCHEMBL8849098 | 0.79 | GHSR (0.45) | LTA4HMAOBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8848575 | 0.78 | MAOB (0.54) | LTA4HMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8848678 | 0.78 | RAB9A (0.53) | NPC1RAB9AL3MBTL1ELANETHRB | |
| SCHEMBL8849336 | 0.78 | TSHR (0.47) | LTA4HNPC1RAB9AL3MBTL1SMN1; SMN2 | |
| SCHEMBL8848626 | 0.77 | LMNA (0.55) | NPC1RAB9AL3MBTL1ELANETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |