Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848588 | 0.99 | LTA4H (0.48) | LTA4HTSHRMAPK1L3MBTL1LMNA | |
| SCHEMBL8848575 | 0.90 | MAOB (0.54) | LTA4HTSHRLMNAALDH1A1MAOB | |
| SCHEMBL8848534 | 0.87 | LTA4H (0.60) | LTA4HTSHRMAPK1L3MBTL1LMNA | |
| SCHEMBL8848714 | 0.84 | HSD17B10 (0.51) | LTA4HTSHRMAPK1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8848858 | 0.83 | LTA4H (0.62) | LTA4HTSHRLMNAALDH1A1NPC1 | |
| SCHEMBL8848642 | 0.82 | HSD17B10 (0.52) | LTA4HTSHRMAPK1L3MBTL1LMNA | |
| SCHEMBL8848904 | 0.82 | SMN1; SMN2 (0.47) | LTA4HTSHRMAPK1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8848620 | 0.81 | LMNA (0.46) | LTA4HTSHRMAPK1L3MBTL1LMNA | |
| SCHEMBL8848788 | 0.81 | MEN1 (0.64) | LTA4HTSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8848741 | 0.81 | MAOB (0.52) | LTA4HL3MBTL1MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | disclosed |