Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.60 |
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | GAA | P10253 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | FHIT | P49789 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | GRM6 | O15303 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560663 | 0.84 | FHIT (0.50) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL5119925 | 0.81 | FHIT (0.72) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL18357823 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL2552064 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL223094 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL9629916 | 0.75 | L3MBTL1 (0.53) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL1605021 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL15331123 | 0.72 | MAPT (0.53) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL5331916 | 0.72 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL13343389 | 0.72 | FHIT (1.00) | ALDH1A1MAPTHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679800-A | DISPERSE DYES AND INTERMEDIATES FOR DISPERSE DYES | CLARIANT FINANCE (BVI) LIMITED (VG) | 1997-10-21 | — | — | US | disclosed |
| US-5132411-A | Blue shades | SANDOZ LTD. (CH) | 1992-07-21 | — | — | US | disclosed |