Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924890 | 0.88 | DGKA (0.53) | DGKAALDH1A1GLATOP2AEPHX2 | |
| SCHEMBL591366 | 0.86 | NAAA (0.57) | DGKAEPHX2DNM1HTR2CNAAA | |
| SCHEMBL16858346 | 0.83 | DGKA (0.47) | DGKAALDH1A1GLATOP2AEPHX2 | |
| SCHEMBL13245883 | 0.83 | ACHE (0.41) | DGKAALDH1A1GLATOP2AEPHX2 | |
| SCHEMBL498980 | 0.82 | — | — | |
| SCHEMBL20589 | 0.81 | DGKA (0.58) | DGKAALDH1A1GLAADRA2AADRA1A | |
| SCHEMBL889155 | 0.81 | ALDH1A1 (0.45) | DGKAALDH1A1GLATOP2AEPHX2 | |
| SCHEMBL25922718 | 0.81 | ALDH1A1 (0.43) | DGKAALDH1A1GLAADRA2AADRA1A | |
| SCHEMBL20251128 | 0.81 | DGKA (0.41) | DGKAALDH1A1GLAADRA2AADRA1A | |
| SCHEMBL8851411 | 0.81 | ALDH1A1 (0.45) | DGKAALDH1A1GLATOP2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-B1 | PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma AG (DE) | 2022-02-23 | — | — | EP | disclosed |
| US-5618814-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating multi-drug resistance and pharmaceutical compositions containing these compounds | DR. KARL THOMAE GMBH (DE) | 1997-04-08 | — | — | US | disclosed |