Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852491 | 0.87 | STAT3 (0.44) | STAT3ADRB2MEN1KMT2ATSHR | |
| SCHEMBL8111823 | 0.84 | STAT3 (0.45) | STAT3ADRB2MEN1KMT2ATSHR | |
| SCHEMBL8559684 | 0.82 | STAT3 (0.43) | STAT3ADRB2MEN1KMT2ATSHR | |
| SCHEMBL7131518 | 0.80 | ADRB2 (0.59) | STAT3ADRB2MEN1KMT2AMAPK1 | |
| SCHEMBL10777266 | 0.79 | MEN1 (0.55) | STAT3ADRB2MEN1KMT2ATSHR | |
| SCHEMBL1345146 | 0.78 | STAT3 (0.65) | STAT3ADRB2MEN1KMT2ATSHR | |
| SCHEMBL9211190 | 0.78 | STAT3 (0.52) | STAT3ADRB2MEN1KMT2ATSHR | |
| SCHEMBL10572110 | 0.78 | KCNH2 (0.60) | ADRB2MEN1KMT2AMAPK1KCNH2 | |
| SCHEMBL10920186 | 0.76 | ALDH1A1 (0.58) | ADRB2MEN1KMT2AMAPK1KCNH2 | |
| SCHEMBL10571665 | 0.76 | ADRB2 (0.53) | ADRB2MEN1KMT2AMAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659038-A | GRAMPOSITIVE/GRAMNEGATIVE MICROBIOCIDES; ANTISEPTICS, HUMAN AND VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
| US-5578604-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |