Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 13/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 4/20 | 0.47 |
| ▸ | PLA2G5 | P39877 | 4/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783600 | 1.00 | LTA4H (0.53) | LTA4HPLA2G2APLA2G4BPLA2G10PLA2G1B | |
| SCHEMBL6554479 | 0.90 | LTA4H (0.45) | LTA4HPLA2G2APLA2G4BPLA2G10PLA2G1B | |
| SCHEMBL11227334 | 0.90 | LTA4H (0.45) | LTA4HPLA2G2APLA2G4BPLA2G10PLA2G1B | |
| SCHEMBL29093210 | 0.89 | LTA4H (0.46) | LTA4HPLA2G2APLA2G4BPLA2G10PLA2G1B | |
| Methacrylic Acid SCHEMBL9189593 | 0.89 | PLA2G4B (0.48) | PLA2G2APLA2G4BPLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL12978503 | 0.85 | PLA2G2A (0.51) | LTA4HPLA2G2APLA2G4BPLA2G10PLA2G1B | |
| SCHEMBL8032383 | 0.84 | LTA4H (0.47) | LTA4HPLA2G2APLA2G4BMLNRNR1I2 | |
| SCHEMBL22574890 | 0.82 | LTA4H (0.47) | LTA4HPLA2G4BMLNRNR1I2ESR1 | |
| SCHEMBL6554541 | 0.81 | ALDH1A1 (0.50) | LTA4HPLA2G4BMLNRNR1I2ESR1 | |
| SCHEMBL31588313 | 0.81 | PLA2G10 (0.52) | PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469778-B1 | Method and composition for improving processability of rubber and plastics | TECHNICAL PROCESSING INC (US) | 1997-06-11 | — | — | EP | disclosed |
| EP-0469778-A1 | Method and composition for improving processability of rubber and plastics | TECHNICAL PROCESSING, INC. (US) | 1992-02-05 | — | — | EP | disclosed |