Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578346 | 1.00 | TSHR (0.36) | TSHRFAAHTRPV1F7F3 | |
| SCHEMBL249672 | 0.89 | — | — | |
| SCHEMBL157037 | 0.89 | — | — | |
| SCHEMBL29955736 | 0.89 | — | — | |
| SCHEMBL28569948 | 0.87 | ARG2 (0.34) | ARG2ALDH1A1 | |
| Ethylene Glycol SCHEMBL8852638 | 0.83 | ALDH1A1 (0.38) | TSHRF7F3HSD17B10ARG2 | |
| SCHEMBL3295244 | 0.82 | FAAH (0.44) | FAAHTRPV1F7F3GMNN | |
| SCHEMBL2619762 | 0.82 | FAAH (0.44) | FAAHTRPV1F7F3GMNN | |
| SCHEMBL1334740 | 0.80 | FAAH (0.48) | FAAHTRPV1F7F3GMNN | |
| SCHEMBL542661 | 0.80 | FAAH (0.48) | FAAHTRPV1F7F3GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665834-A | Method of polymerizing alpha-olefins with boryl zirconocene organic 1,1-dimetallic compound catalysts | THE UNIVERSITY OF TOLEDO (US) | 1997-09-09 | — | — | US | disclosed |
| US-5468889-A | FOR USE AS POLYMERIZATION CATALYSTS | THE UNIVERSITY OF TOLEDO (US) | 1995-11-21 | — | — | US | disclosed |