Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TOP1 | P11387 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2619762 | 1.00 | FAAH (0.44) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL1334737 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL2619763 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL4187797 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL542661 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL542662 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL1334740 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL13320972 | 0.98 | FAAH (0.48) | FAAHTRPV1TERTPTPN1PPARG | |
| SCHEMBL157037 | 0.92 | — | — | |
| SCHEMBL29955736 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608260-B | Method for synthesizing aromatic vinyl trifluoro-methyl sulfide compound by removing boric acid | 江南大学 | 2022-06-10 | — | — | CN | claimed |
| CN-112608260-A | Method for synthesizing aromatic vinyl trifluoro-methyl sulfide compound by removing boric acid | 江南大学 | 2021-04-06 | — | — | CN | claimed |
| US-20220119569-A1 | Curable and Solvent Soluble Formulations and Methods of Making and Using Therof | POLY6 TECHNOLOGIES, INC. | 2022-04-21 | — | — | US | disclosed |
| US-20200062877-A1 | Curable and Solvent Soluble Formulations and Methods of Making and Using Therof | POLY6 TECHNOLOGIES, INC. | 2020-02-27 | — | — | US | disclosed |
| WO-2018156766-A2 | CURABLE AND SOLVENT SOLUBLE FORMULATIONS AND METHODS OF MAKING AND USING THEREOF | POLY6 TECHNOLOGIES, INC. (US) | 2018-08-30 | — | — | WO | disclosed |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-11-05 | — | — | US | disclosed |
| US-8404731-B2 | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors | TRANSTECH PHARMA, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120196906-A1 | Substituted Imidazole Derivatives, Compositions, and Methods of Use as PTPase Inhibitors | TRANSTECH PHARMA, INC. (US) | 2012-08-02 | — | — | US | disclosed |
| US-7820670-B2 | 6-aminoimidazo[1,2-b]pyridazine analogs as rho kinase inhibitors for the treatment of rho kinase-mediated diseases and conditions | ALCON RESEARCH, LTD. (US) | 2010-10-26 | — | — | US | disclosed |
| EP-2209764-A1 | GSM INTERMEDIATES | Janssen Pharmaceutica, N.V. (BE) | 2010-07-28 | — | — | EP | disclosed |
| US-7723369-B2 | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors | TRANSTECH PHARMA, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| WO-2009052341-A1 | GSM INTERMEDIATES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-04-23 | — | — | WO | disclosed |
| EP-1991544-A2 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS PTPASE INHIBITORS | Transtech Pharma, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| US-20080177095-A1 | FUROCHROMAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080153813-A1 | 6-AMINOIMIDAZO[1,2-b]PYRIDAZINE ANALOGS AS RHO KINASE INHIBITORS FOR THE TREATMENT OF RHO KINASE-MEDIATED DISEASES AND CONDITIONS | ALCON MANUFACTURING, LTD. (US) | 2008-06-26 | — | — | US | disclosed |
| US-20070191385-A1 | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors | VTV THERAPEUTICS LLC | 2007-08-16 | — | — | US | disclosed |
| WO-2007089857-A2 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS PTPASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| US-6593480-B2 | Obesity, hyperglycemia | ABBOTT LABORATORIES | 2003-07-15 | — | — | US | disclosed |
| WO-2002070507-A2 | GLYCORTICOID RECEPTOR ANTAGONISTS FOR TREATMENT OF DIABETES | ABBOTT LABORATORIES (US) | 2002-09-12 | — | — | WO | disclosed |
| US-20010041802-A1 | Glucocorticoid receptor antagonists for treatment of diabetes | KARO BIO AB (SE) | 2001-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177095-A1 | FUROCHROMAN DERIVATIVES | CFD, LMAN1, UROD | FAAH 4105/4885TRPV1 584/4885TERT 2687/4885 |
| US-20010041802-A1 | Glucocorticoid receptor antagonists for treatment of diabetes | NR3C1, GPR119, NR3C2 | FAAH 1754/4885TRPV1 2348/4885TERT 4217/4885 |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | FAAH 1491/4885TRPV1 255/4885TERT 4852/4885 |
| US-20070191385-A1 | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors | PTP4A1, PTPRJ, PTP4A2 | FAAH 3723/4885TRPV1 2102/4885TERT 2464/4885 |
| US-20120196906-A1 | Substituted Imidazole Derivatives, Compositions, and Methods of Use as PTPase Inhibitors | PTP4A1, PTPRJ, PTP4A2 | FAAH 3723/4885TRPV1 2102/4885TERT 2464/4885 |
| US-20080153813-A1 | 6-AMINOIMIDAZO[1,2-b]PYRIDAZINE ANALOGS AS RHO KINASE INHIBITORS FOR THE TREATMENT OF RHO KINASE-MEDIATED DISEASES AND CONDITIONS | ROCK2, ROCK1, RHOT2 | FAAH 3192/4885TRPV1 3576/4885TERT 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.