Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853475 | 0.90 | HTR1A (0.49) | HTR1ADRD2NAPRTNOTUMTBXAS1 | |
| SCHEMBL5478146 | 0.82 | HPGD (0.50) | DRD2LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28860367 | 0.76 | HPGD (0.45) | DRD2LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9622292 | 0.75 | ALDH1A1 (0.50) | NAPRTTBXAS1ALDH1A1LMNAKMT2A | |
| SCHEMBL8853482 | 0.75 | TBXAS1 (0.59) | NAPRTTBXAS1KMT2A | |
| SCHEMBL27557354 | 0.75 | TBXAS1 (0.51) | NAPRTNOTUMTBXAS1ALDH1A1RECQL | |
| SCHEMBL29817984 | 0.74 | RECQL (0.50) | NAPRTTBXAS1ALDH1A1KMT2AHTT | |
| SCHEMBL11875125 | 0.74 | ALDH1A1 (0.49) | NAPRTTBXAS1ALDH1A1LMNAHTT | |
| SCHEMBL1161996 | 0.74 | RECQL (0.50) | NAPRTTBXAS1ALDH1A1KMT2AHTT | |
| SCHEMBL21387052 | 0.74 | HSPA5 (0.54) | NAPRTTBXAS1CYP11B1CYP11B2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597926-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |