Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824493 | 0.82 | TBXAS1 (0.50) | TBXAS1LTA4HKMT2APTAFR | |
| SCHEMBL5478152 | 0.81 | LTA4H (0.55) | LTA4H | |
| SCHEMBL11063442 | 0.80 | TBXAS1 (0.62) | TBXAS1LTA4HNAPRT | |
| SCHEMBL8060201 | 0.79 | SRD5A2 (0.58) | LTA4H | |
| Hydrochloric Acid SCHEMBL11068513 | 0.79 | TBXAS1 (0.63) | TBXAS1LTA4HNAPRT | |
| SCHEMBL5651827 | 0.79 | LIPE (0.54) | TBXAS1LTA4HKMT2A | |
| SCHEMBL1601592 | 0.78 | LTA4H (0.63) | TBXAS1LTA4HKMT2APTAFR | |
| SCHEMBL4744549 | 0.77 | KMT2A (0.54) | KMT2A | |
| SCHEMBL11063546 | 0.77 | PPARA (0.56) | TBXAS1 | |
| SCHEMBL11068453 | 0.77 | TBXAS1 (0.65) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597926-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |