Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24125191 | 0.81 | CREBBP (0.57) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL2745305 | 0.81 | CREBBP (0.57) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL4969852 | 0.75 | MAPT (0.51) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL9629696 | 0.75 | CREBBP (0.71) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL9629427 | 0.75 | CREBBP (0.62) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL11034753 | 0.74 | HSD17B10 (0.61) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL31542005 | 0.74 | HSD17B10 (0.53) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL28768922 | 0.74 | HSD17B10 (0.53) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL9024189 | 0.74 | HSD17B10 (0.53) | CREBBPBRD4HSD17B10KDM4ETDP1 | |
| SCHEMBL4325934 | 0.74 | HSD17B10 (0.53) | CREBBPBRD4HSD17B10KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657407-B1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1997-12-10 | — | — | EP | disclosed |
| US-5475164-A | Process for preparing 3-fluoro-4,6-dichlorotoluene | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | disclosed |
| EP-0657407-A1 | Process for the preparation of 3-fluoro-4,6-dichlorotoluene | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |
| EP-0324181-B1 | PROCESS FOR THE PREPARATION OF BENZOTHIAZEPINONE DERIVATIVES | BAYER AG (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4948886-A | Process for the preparation of benzothiazepinone derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-14 | — | — | US | disclosed |
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0324181-A1 | Process for the preparation of benzothiazepinone derivatives | BAYER AG (DE) | 1989-07-19 | — | — | EP | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |