Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 6/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275501 | 0.78 | MMP2 (0.50) | — | |
| SCHEMBL21012489 | 0.76 | OPRM1 (0.45) | RENOPRM1OPRD1CNR2CTSC | |
| SCHEMBL30973624 | 0.76 | MME (0.64) | OPRM1OPRD1 | |
| SCHEMBL8583007 | 0.76 | MME (0.64) | OPRM1OPRD1 | |
| SCHEMBL9956195 | 0.76 | MME (0.64) | OPRM1OPRD1 | |
| SCHEMBL30555017 | 0.73 | MME (0.60) | RENOPRM1OPRD1 | |
| SCHEMBL7999621 | 0.72 | NPY1R (0.60) | RENBACE1 | |
| SCHEMBL7999628 | 0.72 | NPY1R (0.60) | RENBACE1 | |
| SCHEMBL7298969 | 0.72 | NPC1 (0.51) | CTSDBACE1 | |
| SCHEMBL6446490 | 0.72 | NPC1 (0.51) | CTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670675-A | Retroviral protease inhibiting compounds | ABBOTT LABORATORIES (US) | 1997-09-23 | — | — | US | disclosed |