SCHEMBL8854448

SCHEMBL8854448

CSc1cccc(C(F)(F)F)c1S(=O)(=O)OCO[PH](=O)OCOS(=O)(=O)c1c(SC)cccc1C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STK10 O94804 1/20 0.33
SLK Q9H2G2 1/20 0.33
P2RX7 Q99572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854453 0.90 ALDH1A1 (0.32) STK10SLKP2RX7
SCHEMBL8854446 0.88 AR (0.33)
SCHEMBL8854419 0.83 SCN8A (0.36)
SCHEMBL27449559 0.83 PKM (0.30)
SCHEMBL27451470 0.83 BCHE (0.30)
SCHEMBL8729877 0.82 STK10 (0.33) STK10SLKP2RX7
SCHEMBL8854616 0.82 STK10 (0.33) STK10SLKP2RX7
SCHEMBL8854609 0.82 STK10 (0.35) STK10SLKP2RX7
SCHEMBL27544000 0.82 GABRA1 (0.34)
SCHEMBL27465920 0.82 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed