SCHEMBL8854641

SCHEMBL8854641

CCc1cccc(C(F)(F)F)c1S(=O)(=O)OO[PH](=O)OC

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CACNA1C Q13936 1/20 0.33
SCN5A Q14524 1/20 0.33
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
IDO1 P14902 2/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
ALOX5 P09917 1/20 0.30
AR P10275 1/20 0.30
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854611 0.87 GABRA1 (0.35) GABRA1GABRB2CACNA1CSCN5AKMT2A
SCHEMBL8854605 0.87 GABRA1 (0.35) GABRA1GABRB2CACNA1CSCN5AKMT2A
SCHEMBL8854443 0.84 SLC22A12 (0.33) KMT2AGAA
SCHEMBL8854673 0.84 KMT2A (0.34) KMT2AGAAMEN1CYP1A2CYP3A4
SCHEMBL8854712 0.84 KCNK3 (0.38) KMT2AAR
SCHEMBL8854420 0.83 NFE2L2 (0.36) KMT2AGAANR1H2AR
SCHEMBL8854631 0.83 AR (0.33) AR
SCHEMBL8854464 0.83 KEAP1 (0.32)
SCHEMBL8854621 0.82 HCRTR1 (0.32)
SCHEMBL8854462 0.81 FFAR4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed