Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854485 | 0.85 | HSD11B1 (0.40) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8854490 | 0.83 | HSD11B1 (0.39) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8854417 | 0.82 | TUBB4A (0.32) | NFE2L2MEN1KMT2ACCR4ALDH1A1 | |
| SCHEMBL8854639 | 0.81 | ALDH1A1 (0.40) | KDM4EGAATSHRALDH1A1L3MBTL1 | |
| SCHEMBL8854438 | 0.78 | GAA (0.34) | SMN1; SMN2KMT2AGAAALDH1A1L3MBTL1 | |
| SCHEMBL8854521 | 0.77 | KMT2A (0.42) | HSD11B1NFE2L2MEN1KMT2AGAA | |
| SCHEMBL8854556 | 0.77 | SLC40A1 (0.35) | — | |
| SCHEMBL28088043 | 0.76 | TDP1 (0.37) | KDM4EHTR6SMN1; SMN2KMT2ATSHR | |
| SCHEMBL198294 | 0.75 | HSD11B1 (0.46) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL27782725 | 0.75 | POLB (0.30) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693590-A | PLANT GROWTH REGULATOR | ROHM AND HAAS COMPANY (US) | 1997-12-02 | — | — | US | claimed |