SCHEMBL8854673

SCHEMBL8854673

CO[PH](=O)OOS(=O)(=O)c1c(C)cccc1C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
GAA P10253 1/20 0.31
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854443 0.86 SLC22A12 (0.33) KMT2AGAANFE2L2
SCHEMBL8854538 0.86 MEN1 (0.35) KMT2AMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL8854526 0.86 KMT2A (0.35) KMT2AMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL8854420 0.85 NFE2L2 (0.36) KMT2AGAANFE2L2
SCHEMBL8854641 0.84 GABRA1 (0.33) KMT2AMEN1CYP1A2CYP3A4CYP2D6
SCHEMBL8854500 0.83 STK10 (0.33)
SCHEMBL8854712 0.81 KCNK3 (0.38) KMT2ANFE2L2
SCHEMBL8854510 0.81 LMNA (0.30) GAA
SCHEMBL8854631 0.80 AR (0.33)
SCHEMBL8854441 0.79 KMT2A (0.40) KMT2AMEN1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed
US-5670691-A REACTION OF 2-SUBSTITUTED BENZENESULFONATE WITH LITHIUM COMPOUND THEN REACTION WITH ELECTROPHILE TO FORM 2,6-DISUBSTITUTED BENZENESULFONATE ROHM AND HAAS COMPANY (US) 1997-09-23 US disclosed